News

Cellular models can elucidate molecular mechanisms underlying several diseases, reducing animal usage in biomedical sciences and following the guiding principles for animal testing. Now, researchers at the Karolinska Institute and at the Karolinska University published a study entitled “Primary Murine Myotubes as a Model for Investigating Muscular…

A team of research scientists based at the University of Twente Department Of Biomechanical Engineering in Enschede, The Netherlands, is developing a passive arm support device prototype, dubbed A-gear, that runs along the body from the contact surface between the seat and upper legs via the torso and upper…

One of the country’s leading not-for-profit organizations for Duchenne Muscular Dystrophy, CureDuchenne, recently launched a certification program for physical therapists, aiming to equip these members of the health force with specialized training in dealing with patients with DMD. The CureDuchenne Cares Physical Therapist Certification Program is set to begin in 2016,…

Researchers at the University of California published a study entitled “Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal Muscles” in the journal Stem Cell Reports whereby they reveal isolated human muscle stem cells capable of repairing damaged muscles. One of the major problems of treating…

A recent special issue of the BioMed Research International journal was published focusing on the newest clues of the mechanisms behind muscular dystrophies and novel directed therapies for the disease. There are various forms of muscular dystrophy and, as the name implies, they are characterized by wasting of the muscles throughout the…

The causes behind Duchenne muscular dystrophy (DMD) are not fully understood and, as in most muscular dystrophies, no current cure or specific treatment exists. As such, management of affected patients involves corticoids and is directed to the complications of the disease, namely physical therapy for muscle weakness and non-invasive ventilation in case…

In a recent study entitled “Revisiting the dystrophin-ATP connection: How half a century of research still implicates mitochondrial dysfunction in Duchenne Muscular Dystrophy aetiology“, published in the journal Medical Hypotheses, researchers explored the hypothesis that Duchenne Muscular Dystrophy (DMD) is characterised by a systemic mitochondrial…

The Muscular Dystrophy Association (MDA), the world’s leading nonprofit health agency dedicated to find treatments and cures for muscular dystrophy and other neuromuscular diseases recently announced that it will rally along with the Duchenne muscular dystrophy (DMD) community on the World Duchenne Awareness Day. For the first time the…

In a recent paper entitled “Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy”published in the Biochimica et Biophysica Acta (BBA) – Molecular and Cell Biology of Lipids journal, U.S. researchers unveiled a relationship between defective lipid biosynthesis and muscle weakness in Duchenne muscular dystrophy.

In a recent paper published in Scientific Reports entitled “Deletion of integrin α7 subunit does not aggravate the phenotype of laminin α2 chain-deficient mice“, researchers from Sweden have revealed novel insights into the role of dystrophin related proteins towards the progression of muscular dystrophy (MD). Muscular dystrophy is…