PPMD 2024: 4 therapies aiming to slow DMD progression now in trials

Four experimental treatments — deramiocel, sevasemten, satralizumab, and tadalafil — all in clinical testing and all aiming to slow the progression of Duchenne muscular dystrophy (DMD), were spotlighted in a session at last week’s Parent Project Muscular Dystrophy (PPMD) conference. In Duchenne MD, mutations lead to a…

Why each stage of DMD progression is uniquely challenging

“The stages of Duchenne.” I remember seeing this heading on many of the websites I obsessively read when I learned that my three sons, Max, 18, Rowen, 14, and Charlie, 12, had Duchenne muscular dystrophy (DMD). The stages of Duchenne are like a timeline of disease progression. Parent…

The Clinical Progression of Duchenne Muscular Dystrophy

https://www.youtube.com/watch?v=AF4D4TyE9NM&t=6s This video from the Duchenne Foundation outlines the clinical progression of Duchenne muscular dystrophy. It explains that for the first few years of a child’s life, there will be no obvious problems, but as the child ages, problems with mobility will start to appear. Find out about the nine main types of muscular dystrophy.